Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Tetracycline Oral Suspension    25 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    tetracycline  250 mg  CAP   
    Ora-Plus® / Ora-Sweet®  1:1  SYRUP  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Empty contents of capsules into a mortar and triturate to a fine powder.
2. Mix Ora-Plus® and Ora-Sweet® together (1:1) to make vehicle.
3. Gradually levigate powder with vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes May substitute Ora-Plus® / Ora-Sweet® (1:1) with any of the following vehicles:
- Ora-Plus® / Ora-Sweet SF® (1:1)
- Ora-Blend®
- Ora-Blend SF®
- Cherry Syrup; please note recipe requires cherry syrup concentrate diluted 1:4 with simple syrup.

Ora-Sweet SF® and Ora-Blend SF® should not be used in neonates less than or equal to 28 days corrected age.

Stability of formulation will depend on the suspending vehicle used (see Storage/Expiry Section).

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Protect From Light
  Shake Well

Storage/Expiry:Refrigerator: 28 days (Ora-Blend® or Ora-Plus®/ Ora-Sweet® 1:1)
  Refrigerator: 10 days (Ora-Blend SF® or Ora-Plus®/ Ora-Sweet SF® 1:1)
  Refrigerator: 7 days (Cherry Syrup)
  Room Temperature: 28 days (Ora-Blend® or Ora-Plus®/ Ora-Sweet® 1:1)
  Room Temperature: 7 days (Ora-Blend SF® or Ora-Plus®/ Ora-Sweet SF® 1:1)
  Room Temperature: 2 days (Cherry Syrup)

Last Date Revised: 8-Jun-11

References:Allen LV, & Erickson MA. Stability of bethanechol chloride, pyrazinamide, quinidine sulfate, rifampin, and tetracycline hydrochloride in extemporaneously compounded oral liquids. Am J Health-Syst Pharm 1998; 55:1804-1809.
 
Trissel LA. Trissel’s™ Stability of compounded formulations. 4th ed. Washington, DC: American Pharmacists Association; 2009.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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