Recipe - Compounding Worksheet
Unauthorized distribution, copying or disclosure prohibited.
These recipes are intended for use by the pharmacy manufacturing departments only.
Gabapentin Oral Suspension   100 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    gabapentin  400 mg  CAP   
    Ora-Plus® / Ora-Sweet®  1:1  SYRUP  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Empty contents of capsules into mortar and triturate to a FINE powder.
2. Mix Ora-Plus® and Ora-Sweet® together (1:1) to make vehicle.
3. Gradually levigate powder with vehicle until a uniform liquid is formed. Mix THOROUGHLY after each addition of diluent.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes Ora-Blend® can be used instead of Ora-Plus® / Ora-Sweet® (1:1).

Crystallization may occur if powder is coarsely ground or if final product is refrigerated.

Based on pharmacy experience, storage in fridge may result in crystallization, therefore room temperature storage is recommended, even though references determined suspension to be stable for 91 days refrigerated (see Reference Section).

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Shake Well
  Store at Room Temperature

Storage/Expiry:Room Temperature: 56 days

Last Date Revised: 8-Jun-11

References:Formulations: Gabapentin 100-mg/mL oral liquid. International Journal of Pharmaceutical Compounding. 2006; 10(6):456.

Nahata MC. Development of two stable oral suspensions for gabapentin. Pediatr Neurol 1999; 20:195-197.
Recommended a stability of 91 days refrigerated or 56 days room temperature with Ora-Plus®/ Ora-Sweet® (1:1) or Methylcellulose 1%/ Simple Syrup.
  Reference article from Pediatric Neurology 1999 is by same author.
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


This content is provided for general information purposes only. It is not intended to replace consultations with a health care professional or to provide medical advice, diagnosis or treatment. Always seek the advice of a physician or other qualified health care provider with any medical or health questions. Alberta Health Services accepts no responsibility for any modification or redistribution of this document and is not liable for any actions taken by individuals based on the information provided, or for any inaccuracies, errors, or omissions in the information in this document. These recipes are to be used as a reference and are not intended to be master formulation records. Not all recipes may be compliant with NAPRA or other standards.