Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Dantrolene Sodium Oral Suspension   5 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    dantrolene  25 mg  CAP   
    Citric acid monohydrate, USP    PWD   
    Water, sterile        
    Simple syrup       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Empty contents of capsules into a mortar and triturate to a fine powder.
2. Gradually levigate powder with simple syrup until a liquid is formed.
3. Dissolve citric acid powder in water. Add to powder/ simple syrup mixture. Mix well.
3. Pour into a graduated cylinder.
4. Rinse mortar and qs to final volume with simple syrup.
5. Transfer to final container and label.

Notes Room temperature storage provides a more uniform suspension.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 30 days

Last Date Revised: 18-Aug-16

References:
  Dantrolene 5 mg/mL oral suspension recipe (last updated April 2007).
Assigned a stability of 30 days at room temperature.
SickKids Compounding Service [online recipes]. Toronto, ON: The Hospital for Sick Children. c1999 [current date]. Available from: http://www.sickkids.ca/Pharmacy/Compounding-Service/index.html
 
SickKids Compounding Service [online recipes]. Toronto, ON: The Hospital for Sick Children. c1999 [current date]. Available from: http://www.sickkids.ca/Pharmacy/Compounding-Service/index.html
  Recommended a stability of 30 days at room temperature.
SickKids Compounding Service [online recipes]. Toronto, ON: The Hospital for Sick Children. c1999 [current date]. Available from: http://www.sickkids.ca/Pharmacy/Compounding-Service/index.html

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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