Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Pentoxifylline Oral Suspension   20 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    pentoxifylline  400 mg  XL TAB   
    Water, sterile       qs to  
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Gradually levigate powder with water until a liquid is formed.
3. Pour into a graduated cylinder.
4. Rinse mortar and qs to final volume with water.
5. Transfer to final container and label.

Notes Alternatively, to improve the consistency of the final product:
- a blender could be used to aid in the preparation, OR
- soak tablets in some water for 2 to 3 hours, then stir to make a paste, QS to final volume and let stand for approximately 24 hours at room temperature before dispensing, OR
- Place product into plastic bottle and shake for approximately 5 minutes.

Pentoxifylline SR tablets can be used instead of XL tablets to prepare the suspension.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 91 days

Last Date Revised: 19-Jun-19

References:Formulations: Pentoxifylline 20 mg/mL oral suspension. International Journal of Pharmaceutical Compounding 2008; 12(1):70.

Abdel-Rahman S, Nahata MC. Stability of pentoxifylline in an extemporaneously prepared oral suspension. Am J Health Syst Pharm 1997 (Jun 1); 54(11):1301-1303.
Pentoxifylline 400 mg extended release tablets crushed and mixed with water:
- stored in glass and plastic prescription bottles
- stable for 91 days at room temperature or refrigerated

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

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