Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Amitriptyline Oral Suspension (LOW STRENGTH)   1 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    amitriptyline  25 mg  TAB   
    glycerin  100%  PO SOLN   
    Simple syrup       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Levigate powder with glycerin until a paste is formed.
3. Gradually levigate paste with simple syrup until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with simple syrup.
6. Transfer to final container and label.

Notes NOTE: Stability-indicating analytical studies not used.

Assign expiry date using USP 795 Guidelines.
795 guidelines: Water-Containing Formulations:
The beyond-use date is not later than 14 days for liquid preparations when stored at cold temperature between 2C - 8C.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Note Strength
  Protect From Light
  Refrigerate
  Shake Well

Storage/Expiry:Refrigerator: 14 days

Last Date Revised: 9-Aug-16

References:Formulations: Amitriptyline hydrochloride 1 mg/mL oral liquid and gel. International Journal of Pharmaceutical Compounding 1999; 3:218.
 
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.
 
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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