Recipe - Compounding Worksheet
Unauthorized distribution, copying or disclosure prohibited.
These recipes are intended for use by the pharmacy manufacturing departments only.
Ketamine Oral Solution (prepared from injection)    10 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    ketamine  50 mg/mL  INJ   
    Cherry syrup      qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Withdraw required amount of ketamine from vial(s).
2. Pour into a graduated cylinder.
3. QS to final volume with cherry syrup.
4. Transfer to final container and label.

Notes Study in reference used strawberry flavored glucose vehicle. Cherry syrup was selected instead of strawberry flavored glucose since it has a similar pH of 4.5 and is readily available.

Please note that this recipe requires the ready-to-use cherry syrup and NOT the cherry syrup concentrate. If your site uses the concentrate, it MUST be diluted before using in the recipe.

Recipe using ketamine powder should be prepared when ketamine injectable is in limited supply or not available.

Packaging: 100 mL Amber Plastic Bottle

Auxiliary Labels: Refrigerate

Storage/Expiry:Refrigerator: 8 weeks

Last Date Revised: 22-Aug-16

References:Funk W. Jakob W. Riedl T. Taeger K. Oral preanaesthetic medication for children: double-blind randomized study of a combination of midazolam and ketamine vs. midazolam or ketamine alone. Br J Anaesth 2000; 84(3):335-340.
Study prepared ketamine 12 mg/mL oral solution. We have decided on a 10 mg/mL solution for ease of dosing.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

This content is provided for general information purposes only. It is not intended to replace consultations with a health care professional or to provide medical advice, diagnosis or treatment. Always seek the advice of a physician or other qualified health care provider with any medical or health questions. Alberta Health Services accepts no responsibility for any modification or redistribution of this document and is not liable for any actions taken by individuals based on the information provided, or for any inaccuracies, errors, or omissions in the information in this document. These recipes are to be used as a reference and are not intended to be master formulation records. Not all recipes may be compliant with NAPRA or other standards.