Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Sodium Citrate/ Citric Acid (Modified Shohl's Solution)   provides 1 mEq/mL of sodium and equivalent to 1 mEq/mL of bicarbonate
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    sodium citrate dihydrate    PWD   
    Citric acid monohydrate, USP    PWD   
    Water, sterile       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Weigh out powders.
2. Dissolve powders in a portion of the water.
3. QS to final volume with water.
4. Transfer to final container and label.

Notes 5 mL contains: 500 mg sodium citrate dihydrate and 334 mg citric acid monohydrate (same as PMS-Dicitrate commercial product).

Sodium citrate dihydrate crystals or powder can be used.

Ingredient alternatives (original recipe ingredients preferred):
Sodium citrate dihydrate 10 g = sodium citrate anhydrous 8.7 g
Citric acid monohydrate 6.68 g = citric acid anhydrous 6.1 g

Contains sodium 1 mEq/mL and is equivalent to bicarbonate 1 mEq/mL.

Packaging: 100 mL Amber Plastic Bottle

Auxiliary Labels: Refrigerate
  Shake Well

Storage/Expiry:Refrigerator: 14 days

Last Date Revised: 6-Feb-12

References:Formulations: Shohl's solution, Modified (Albright's Solution). International Journal of Pharmaceutical Compounding 2005; 9(4):316.
  Sodium Citrate and Citric Acid Monograph
Lexi-Comp [database on the Internet]. Hudson, OH: Lexi-Comp Inc. c.1978 - [current date]. Available from:

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

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