Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Propafenone Oral Suspension   1.5 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    propafenone  150 mg  TAB   
    Pomegranate syrup    SYRUP  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablet and triturate to a fine powder.
2. Gradually levigate powder with syrup until a liquid is formed.
3. Pour into a graduated cylinder.
4. Rinse mortar and QS to final volume with syrup.
5. Transfer to final container and label.

Notes If pomegranate syrup is not available, cherry syrup can be used and a 14 day refrigerated expiry date can be arbitrary assigned based on USP 795 guidelines for compounding of non-sterile preparations.

If cherry syrup is used, ready-to-use cherry syrup should be used, NOT the cherry syrup concentrate. If your site uses the concentrate, it MUST be diluted before using in the recipe.

Packaging: 100 mL Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 90 days

Last Date Revised: 23-Aug-16

References:Olguin HJ. Perez CF. Perez JF. Mendiola BR. Portugal MC. Chavez JB. Bioavailability of an extemporaneous suspension of propafenone made from tablets. Biopharm Drug Dispos 2006; 27:241-245.

Formulations: Propafenone 1.5 mg/mL oral liquid. International Journal of Pharmaceutical Compounding 2008; 12(5):455.

USP 795 guidelines for Pharmaceutical Compounding - Nonsterile Preparations.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

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