Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Midazolam Oral Solution (LOW STRENGTH)   1 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    midazolam  5 mg/mL  INJ   
    Simple syrup        
    Water, sterile       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, mix required amount of midazolam injection and simple syrup.
2. Pour into a graduated cylinder.
3. Rinse mortar and qs to final volume with water.
4. Transfer to final container and label.

Notes Orange extract 0.12 mL can be added if desired.

Can substitute midazolam USP powder for injectable midazolam.

Arbitrary expiration date of 14 days refrigerated can be assigned based on USP 795 guidelines.

Packaging:  Amber Glass Bottle

Auxiliary Labels: Note Strength
  Store at Room Temperature

Storage/Expiry:Refrigerator: 14 days (prepared from powder)
  Room Temperature: 102 days (prepared from injectable solution)

Last Date Revised: 24-Jan-14

References:Walker SE. Grad HA. Haas DA. Mayer A. Stability of parenteral midazolam in an oral formulation. Anesth Prog 1997, 44(1):17-22.
 
USP 34 NF 29, 2nd Volume 1. Chapter 795: Pharmaceutical compounding Nonsterile preparations. Rockville, MD, USA: United States Pharmacopeial Convention; 2010

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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