Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Labetalol Oral Suspension (LOW STRENGTH)   10 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    labetalol  200 mg  TAB   
    Simple syrup       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Gradually levigate powder with simple syrup until a liquid is formed.
3. Pour into a graduated cylinder.
4. Rinse mortar and qs to final volume with simple syrup.
5. Transfer to final container and label.

Notes May substitute sterile water, apple juice, grape juice, or orange juice for simple syrup. Same stability and storage conditions.

Refrigerated storage preferred as testing for microbial growth was not completed.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Note Strength
  Refrigerate
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 4 weeks (28 days)

Last Date Revised: 23-Aug-16

References:Nahata MC. Stability of labetalol hydrochloride in distilled water, simple syrup, and three fruit juices. Annals of Pharmacotheraoy 1991; 25:465-469.
 
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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