||1. Empty contents of capsule into a mortar.
2. Gradually levigate powder with water until a liquid is formed.
3. Pour into a graduated cylinder.
4. Rinse mortar and qs to final volume with water.
5. Transfer to final container and label.
||May substitute apple juice or applesauce instead of water.
A 2.5 mg capsule may be used to prepare a 21 mcg/mL suspension, or a 5 mg capsule may be used to prepare a 42 mcg/mL suspension.
Can be packaged in amber glass bottles or polyethylene terephthalate (PET) containers.
|| Amber Glass Bottle
|Storage/Expiry:||Refrigerator: 48 hours|
||Room Temperature: 24 hours
|Last Date Revised:
|References:||Trissel LA. Trissel's stability of compounded formulations. Washington DC. Am Ph Assoc. 3rd ed, 2005:377 |
Allen LV, Stiles ML, Prince SJ, McLaury HJ, Sylvestri MF. Stability of ramipril in water, apple juice, and applesauce. Am J Health-Syst Pharm 1995; 52:2433-2436.