Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Ranitidine Oral Suspension    15 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    ranitidine  150 mg  TAB   
    Water, sterile        
    Simple syrup      qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Gradually add water. Mix well.
3. Pour into a graduated cylinder.
4. QS to final volume with simple syrup.
5. Transfer to final container and label.

Notes To be prepared ONLY in the event that the commercial product is NOT available.

Ranitidine powder can be used in place of ranitidine tablets.

The final product can be stored at room temperature or refrigerated. See Storage/ Expiry section.

Packaging: 100 mL Amber Plastic Bottle

Auxiliary Labels: Protect From Light
  Shake Well
  Store at Room Temperature

Storage/Expiry:Refrigerator: 14 days
  Room Temperature: 7 days

Last Date Revised: 24-Aug-16

References:Allen, Loyd V Jr. Ranitidine Hydrochloride 15-mg/mL oral liquid. International Journal of Pharmaceutical Compounding 2007 (Mar/Apr); 11(2):161.

Karnes HT, Harris SR, Garnett WR, March C. Concentration uniformity of extemporaneously prepared ranitidine suspension. Am J Hosp Pharm 1989; 46(2):304.

Pharmacy, IWK Health Centre, Halifax, NS. Ranitidine Oral Syrup 15-mg/mL, last revised July 8, 2011.

Ferreira MO, et al. Stability of ranitidine hydrochloride in different aqueous solutions. Eur J Hosp Pharm 2004; 10:60-63

MedSask (medical information service), Saskatoon, Saskatchewan. Ranitidine oral suspension March 2015.
Woods DJ. Formulation in pharmacy practice. 2nd edition, Dunedin, New Zealand. Available from:

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

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