Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Hydrocortisone Ointment in Petrolatum    1%
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    hydrocortisone    PWD   
    petrolatum  100%  UNG   
Recipe Total Quantity:
Final Quantity Desired: g

Directions: 1. Weigh out hydrocortisone powder and white petrolatum.
2. Levigate the hydrocortisone powder with a small amount of petrolatum.
3. Gradually add the rest of the petrolatum and mix thoroughly.
4. Transfer to ointment jar and label.

Notes To be prepared ONLY in the event that the commercial product is NOT available.

Assign expiry date using USP 795 Guidelines, since no stability data available.
USP 795 guidelines - Solid Formulations:
"Where the manufactured drug product is the active ingredient source - not later than 25% of the time remaining until the preparation expiration date or 6 months, whichever is earlier.
Where USP or NF is the active ingredient source - 6 months"

THIS FORMULATION IS NOT BASED ON LITERATURE, but is from unpublished data, historical use or physician/pharmacy experience.

Packaging:  Ointment Jar

Auxiliary Labels: For External Use Only
  Store at Room Temperature

Storage/Expiry:Room Temperature: 6 months

Last Date Revised: 24-Jan-14

References:Gupta VD. Effect of vehicles and other active ingredients on stability of hydrocortisone. J Pharm Sci 1978; 67(3): 299-302.
 
USP 34 NF 29, 2nd Volume 1. Chapter 795: Pharmaceutical compounding Nonsterile preparations. Rockville, MD, USA: United States Pharmacopeial Convention; 2010

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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