Recipe - Compounding Worksheet
Unauthorized distribution, copying or disclosure prohibited.
These recipes are intended for use by the pharmacy manufacturing departments only.
Busulfan Oral Suspension   2 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    busulfan  2 mg  TAB   
    Simple syrup      qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Refer to the AHS Hazardous Medication Handling Guide for more information.

1. In a glass mortar, crush tablets and triturate to a fine powder.
2. Gradually levigate powder with simple syrup until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with simple syrup.
6. Transfer to final container and label.

Notes No stability data in plastic syringes.

Packaging:  Amber Glass Bottle

Auxiliary Labels: Antineoplastic Agent
  CHEMOTHERAPY Dispose of Properly
  Hazardous medication - use safe handling precautions
  Protect From Light
  Shake Well

Storage/Expiry:Refrigerator: 30 days
  Room Temperature: 3 days

Last Date Revised: 16-May-18

References: AHS Hazardous Medication Handling information available on Insite:

Allen LV. Busulfan oral suspension. U.S. Pharmacist 1990 (Nov); 15(11):94-95.

Formulations: Busulfan 2 mg/mL oral liquid. International Journal of Pharmaceutical Compounding 2007 (Mar/Apr); 11(2):155.

Written communication from Glaxo Wellcome to Alberta Children's Hospital Drug Information Pharmacist; April 22, 1998. Extemporaneous Preparation of a MyleranŽ (Busulfan) Suspension.
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

This content is provided for general information purposes only. It is not intended to replace consultations with a health care professional or to provide medical advice, diagnosis or treatment. Always seek the advice of a physician or other qualified health care provider with any medical or health questions. Alberta Health Services accepts no responsibility for any modification or redistribution of this document and is not liable for any actions taken by individuals based on the information provided, or for any inaccuracies, errors, or omissions in the information in this document. These recipes are to be used as a reference and are not intended to be master formulation records. Not all recipes may be compliant with NAPRA or other standards.