Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Methadone Sublingual Solution    40 mg/mL *Note Strength*
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    methadone    PWD   
    Water, sterile        
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Dissolve methadone in required quantity of water.
2. Mix well.
3. Transfer to final container and label.

Notes This strength is non-formulary.
Refer to Methadone oral solution in AHS Provincial Formulary.

CAUTION: Should be used in Adult Palliative Care Service ONLY.

THIS FORMULATION IS NOT BASED ON LITERATURE, but is from unpublished data, historical use, or physician/pharmacy experience.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Note Strength
  Protect From Light
  Refrigerate

Storage/Expiry:Refrigerator: 7 days

Last Date Revised: 23-Aug-16

References:Hagen NA. Fisher K. Stiles C. Sublingual methadone for the management of cancer-related breakthrough pain: a pilot study. Journal of Palliative Medicine 2007; 10(2):331-337.
Concentrations/ formulation in reference are different from recipe.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


This content is provided for general information purposes only. It is not intended to replace consultations with a health care professional or to provide medical advice, diagnosis or treatment. Always seek the advice of a physician or other qualified health care provider with any medical or health questions. Alberta Health Services accepts no responsibility for any modification or redistribution of this document and is not liable for any actions taken by individuals based on the information provided, or for any inaccuracies, errors, or omissions in the information in this document. These recipes are to be used as a reference and are not intended to be master formulation records. Not all recipes may be compliant with NAPRA or other standards.