Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Hydrocortisone 1% and Clotrimazole 1% Cream    1:1
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    hydrocortisone  1%  CRM   
    clotrimazole  1%  CRM   
Recipe Total Quantity:
Final Quantity Desired: g

Directions: 1. Levigate creams together until a uniform mixture is obtained.
2. Transfer to ointment jar and label.

Notes Hydrocortisone 1% cream is Non-Formulary with a Therapeutic Interchange.
Refer to Hydrocortisone 1% cream in AHS Provincial Formulary.

Assign expiry date using USP 795 Guidelines, since no stability data available.
USP 795 guidelines - Solid Formulations:
"Where the manufactured drug product is the active ingredient source - not later than 25% of the time remaining until the preparation expiration date or 6 months, whichever is earlier.
Where USP or NF is the active ingredient source - 6 months"

THIS FORMULATION IS NOT BASED ON LITERATURE, but is from unpublished data, historical use or physician/pharmacy experience.

Packaging:  Ointment Jar

Auxiliary Labels: For External Use Only
  Store at Room Temperature

Storage/Expiry:Room Temperature: 6 months

Last Date Revised: 24-Jan-14

References:
 
USP 34 NF 29, 2nd Volume 1. Chapter 795: Pharmaceutical compounding Nonsterile preparations. Rockville, MD, USA: United States Pharmacopeial Convention; 2010

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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