Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Mycophenolate Mofetil Oral Suspension in Cherry Syrup   100 mg/mL *Note Strength*
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    mycophenolate mofetil  250 mg  CAP   
    Water, sterile       to wet tablets 
    Cherry syrup      qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: HAZARDOUS - Potential
Refer to the AHS Hazardous Medication Handling Guide for more information.

1. Empty contents of capsules into a mortar and triturate to a fine powder.
2. Wet the powder with a sufficient amount of water and levigate to a smooth paste.
3. Gradually add cherry syrup until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with cherry syrup.
6. Transfer to final container and label.

Notes A commercial 200 mg/mL oral formulation is available. Strength of compounded formulation is different than the commercial preparation.
This strength is non-formulary.
Refer to Mycophenolate suspension in AHS Provincial Formulary.

This recipe should only be prepared when the commercial product is not suitable for the patient.

Please note recipe requires the ready-to-use cherry syrup and NOT the cherry syrup concentrate. If your site uses the concentrate, it MUST be diluted before using in the recipe.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Hazardous medication - use safe handling precautions
  Note Strength

Storage/Expiry:Refrigerator or Room Temperature: 121 days

Last Date Revised: 2-Dec-19

References: AHS Hazardous Medication Handling information available on Insite: http://insite.albertahealthservices.ca/17382.asp

Anaizi NH, Swenson CF, Dentinger PJ. Stability of mycophenolate mofetil in an extemporaneously compounded oral liquid. Am J Health-Syst Pharm 1998 (May); 55:926-929.
 
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.
 
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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