Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Voriconazole Oral Suspension    40 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    voriconazole  200 mg  TAB   
    Ora-Plus® / Ora-Sweet®  1:1  SYRUP  qs to  
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: HAZARDOUS - Reproductive
Refer to the AHS Hazardous Medication Handling Guide for more information.

1. In a mortar, crush tablets and triturate to a fine powder.
2. Mix Ora-Plus® and Ora-Sweet® together (1:1) to make vehicle.
3. Gradually levigate powder with vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes To be prepared ONLY in the event that the commercial product is NOT available or unsuitable.

May substitute Ora-Plus® / Ora-Sweet® (1:1) with any of the following vehicles:
- Ora-Blend®
- Water / Ora-Plus® (1:3)

Stable at room temperature or refrigerated, but storage in refrigerated conditions preferred.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Hazardous medication - use safe handling precautions
  Refrigerate
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 30 days

Last Date Revised: 17-May-18

References: AHS Hazardous Medication Handling information available on Insite: http://insite.albertahealthservices.ca/17382.asp

Nguyen KQ. Hawkins MG. Taylor IT. Wiebe VJ. Tell LA. Stability and uniformity of extemporaneous preparations of voriconazole in two liquid suspension vehicles at two storage temperatures. American Journal of Veterinary Research 2009; 70 (7) 908-914.
 
Nahata MC, Pai VB. Pediatric drug formulations. 6th ed. Cincinnati, Ohio: Harvey Whitney Books Company; 2011.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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