Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Ciprofloxacin Oral Suspension in Ora-Plus®/ Ora-Sweet®   50 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    ciprofloxacin  500 mg  TAB   
    Ora-Plus® / Ora-Sweet®  1:1  SYRUP  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Mix Ora-Plus® and Ora-Sweet® together (1:1) to make vehicle.
3. Gradually levigate powder with vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes To be prepared ONLY in the event that the commercial product is NOT available or unsuitable.

Strength of compounded formulation is different than the commercial preparation.
This strength is non-formulary.
Refer to Ciprofloxacin suspension in AHS Provincial Formulary.

May substitute Ora-Plus® / Ora-Sweet® (1:1) with any of the following vehicles:
- Ora-Blend®
- Methylcellulose 1%/ Simple Syrup (1:1)

Other strengths of ciprofloxacin tablets can be used. Adjust quantity as required to make a 50 mg/mL suspension.

Can be stored refrigerated (preferable) or room temperature.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Refrigerate
  Shake Well

Storage/Expiry:Refrigerator: 91 days (preferred storage)
  Room Temperature: 70 days

Last Date Revised: 24-Jan-14

References:Nahata MC. Morosco RS. Hipple TF. Development of stable oral suspensions of ciprofloxacin. Journal of Applied Therapeutic Research 2000; 3(1): 61-65.
Nahata MC, Pai VB. Pediatric drug formulations. 6th ed. Cincinnati, Ohio: Harvey Whitney Books Company; 2011.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

This content is provided for general information purposes only. It is not intended to replace consultations with a health care professional or to provide medical advice, diagnosis or treatment. Always seek the advice of a physician or other qualified health care provider with any medical or health questions. Alberta Health Services accepts no responsibility for any modification or redistribution of this document and is not liable for any actions taken by individuals based on the information provided, or for any inaccuracies, errors, or omissions in the information in this document. These recipes are to be used as a reference and are not intended to be master formulation records. Not all recipes may be compliant with NAPRA or other standards.