Recipe - Compounding Worksheet
Unauthorized distribution, copying or disclosure prohibited.
These recipes are intended for use by the pharmacy manufacturing departments only.
cloBAZam Oral Suspension   1 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    clobazam  10 mg  TAB   
    Oral Mix™    PO SOLN  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: HAZARDOUS - REPRODUCTIVE
Refer to the AHS Hazardous Medication Handling Guide for more information.

1. In a mortar, crush tablets and triturate to a fine powder.
2. Add approximately 10 mL of vehicle to make a paste.
3. Gradually levigate paste with vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Packaging:  Amber Plastic or Glass Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Protect From Light
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 91 days

Last Date Revised: 29-Jul-21

References:Ziegler BE, Walsh A, Walker SE, Law S, Lingertat-Walsh K, Sales P. Stability of Clobazam 1mg/mL in Extemporaneously Compounded Oral Suspensions Using Oral Mix Vehicle in PET, PVC, Glass Bottles and Plastic Unit-Dose Syringes. Can J Hosp Pharm. 2014 Jan-Feb;67(1):70.
Available from: https://www.cjhp-online.ca/index.php/cjhp/article/view/1325/1862
Also available from: https://www.medisca.com/Pages/Studies/pdf-files/publications/oral/Extemporaneously%20compounded%20Clobazam%201mg-mL%20Poster.pdf
  No formal stability study conducted of clobazam suspension prepared with Ora-Blend or Ora-Plus or other commercial bases.
Recipe is a suggested option.
Woods DJ. Formulation in pharmacy practice. 2nd edition, Dunedin, New Zealand. Available from:
http://www.fshealth.gov.za/subsites/DWoods/home.html

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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