Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Phytonadione (Vitamin K1) Oral Suspension (prepared from tablets)   1 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    phytonadione   5 mg   TAB   
    Methylcellulose solution  1%     
    Water, sterile        
    Sorbitol 70%      qs to  
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Gradually levigate powder with water and methylcellulose solution until a liquid is formed.
3. Pour into a graduated cylinder.
4. Rinse mortar and qs to final volume with sorbitol 70% solution. Mix well.
5. Transfer to final container and label.

Notes Phytonadione 5 mg tablets (Mephyton) are available through Health Canada's Special Access Programme.

This recipe should be compounded instead of the recipe prepared from injection whenever there is a limited supply/shortage of phytonadione injectable.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Refrigerate
  Shake Well

Storage/Expiry:Refrigerator: 3 days

Last Date Revised: 2-Jun-14

References:
 
Nahata MC, Pai VB. Pediatric drug formulations. 6th ed. Cincinnati, Ohio: Harvey Whitney Books Company; 2011.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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