Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Propranolol Oral Suspension   5 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    propranolol  40 mg  TAB   
    Ora-Plus®/ Ora-Sweet SF®   1:1  SYRUP  qs to  
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Mix Ora-Plus® and Ora-Sweet SF® together (1:1) to make vehicle.
3. Gradually levigate powder with vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes Ora-Blend SF® can be used instead of Ora-Plus® / Ora-Sweet SF® (1:1).

Ora-Sweet SF® and Ora-Blend SF® should not be used in neonates less than or equal to 28 days corrected age.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Note Strength
  Refrigerate
  Shake Well

Storage/Expiry:Refrigerator: 120 days
  Room Temperature: 60 days

Last Date Revised: 23-Aug-16

References:Ensom MHH. Kendrick J. Rudolph S. Decarie D. Stability of propranolol in extemporaneously compounded suspensions. CJHP 2013; 66(2):118-124.
Recommended a stability of 120 days refrigerated and at room temperature; but on day 70 the suspension stored at room temperature developed a slight change in colour from green to yellowish green.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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