||1. In a mortar, crush tablets and triturate to a fine powder.
2. Gradually levigate sequentially with ethanol, methylcellulose powder, parabens and lastly, glycerin.
3. Pour into a graduated cylinder.
4. Rinse mortar and qs to final volume with water.
5. Transfer to final container and label.
||See recipe for Parabens 10% oral solution.
Modified from original recipe which employed 95% ethanol (ethyl alcohol).
Ethanol-containing extemporaneous preparations are not recommended to be used in the neonatal or pediatric populations; as this formulation contains 5% ethanol, clinical appropriateness for your patient should be reviewed.
|| Amber Glass Bottle
||Protect From Light|
|Storage/Expiry:||Refrigerator: 30 days|
|Last Date Revised:
|References:||Woods D. Formulation in pharmacy practice. 2nd ed. 2001. Dunedin, New Zealand: HealthCare Otago; Available from www.Pharminfotech.co.nz.|
Trissel LA. Trissel’s™ Stability of compounded formulations. 4th ed. Washington, DC: American Pharmacists Association; 2009.