Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Levodopa/ Carbidopa Rectal Suspension (LOW STRENGTH)   50 mg-12.5 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    levodopa - carbidopa  100 mg - 25 mg  TAB   
    Water, sterile        
    glycerin  100%  PO SOLN   
    Citric acid monohydrate, USP    PWD   
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Dissolve citric acid in water.
3. Mix glycerin and citrated water mixture together.
4. Gradually levigate powder with glycerin citrate vehicle. Mix well.
5. Pour into a graduated cylinder.
6. Rinse mortar and qs to final volume with vehicle.
7. Transfer to final container and label.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Note Strength
  Shake Well

Storage/Expiry:Refrigerator: 35 days
  Room Temperature: 10 days

Last Date Revised: 18-Oct-21

References:Donnelly RF. Stability of levodopa/carbidopa rectal suspensions. Hosp Pharm 2016; 51(11): 915-921

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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