Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Methylcellulose Oral Suspension (with Sodium Benzoate)   1%
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    Methylcellulose   1500 mPA-s  PWD   
    sodium benzoate    PWD   
    Water, sterile       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Refrigerate water overnight.
2. Dissolve the sodium benzoate powder in boiling water (20% of the total quantity of sterile water).
3. Add the methylcellulose powder and stir well for 2 to 3 minutes (use blender if available).
4. Add ice cold water (80% of the total quantity of sterile water), carefully but quickly, and stir or blend well for 10 minutes.
5. Transfer to bottle. Refrigerate overnight, or for a minimum of 4 hours, until creamy thick white liquid converts to a clear gel.

Notes Mixture is initially cloudy but it should be a completely clear viscous solution with adequate cooling/refrigeration and time.

Shake gently prior to use.

Dust mask, gloves and goggles are recommended for individuals who are sensitive to dust and any others who are working with methylcellulose for an extended time.

Store product at room temperature or refrigerated.

Packaging: (preferred) or Amber Plastic Bottle Amber Glass Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 6 months (Discard 30 days after opening)

Last Date Revised: 27-Jan-16

References:
  Methylcellulose 1% SickKids recipe (last updated April 2007)
SickKids Compounding Service [online recipes]. Toronto, ON: The Hospital for Sick Children. c1999 [current date]. Available from: http://www.sickkids.ca/Pharmacy/Compounding-Service/index.html

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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