Recipe - Compounding Worksheet
Unauthorized distribution, copying or disclosure prohibited.
These recipes are intended for use by the pharmacy manufacturing departments only.
Methylcellulose Oral Suspension (with Sodium Benzoate)   1%
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    Methylcellulose   1500 mPA-s  PWD   
    sodium benzoate    PWD   
    Water, sterile       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Refrigerate water overnight.
2. Dissolve the sodium benzoate powder in boiling water (20% of the total quantity of sterile water).
3. Add the methylcellulose powder and stir well for 2 to 3 minutes (use blender if available).
4. Add ice cold water (80% of the total quantity of sterile water), carefully but quickly, and stir or blend well for 10 minutes.
5. Transfer to bottle. Refrigerate overnight, or for a minimum of 4 hours, until creamy thick white liquid converts to a clear gel.

Notes Mixture is initially cloudy but it should be a completely clear viscous solution with adequate cooling/refrigeration and time.

Shake gently prior to use.

Dust mask, gloves and goggles are recommended for individuals who are sensitive to dust and any others who are working with methylcellulose for an extended time.

Store product at room temperature or refrigerated.

Packaging: (preferred) or Amber Plastic Bottle Amber Glass Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 6 months (Discard 30 days after opening)

Last Date Revised: 27-Jan-16

  Methylcellulose 1% SickKids recipe (last updated April 2007)
SickKids Compounding Service [online recipes]. Toronto, ON: The Hospital for Sick Children. c1999 [current date]. Available from:

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist

This content is provided for general information purposes only. It is not intended to replace consultations with a health care professional or to provide medical advice, diagnosis or treatment. Always seek the advice of a physician or other qualified health care provider with any medical or health questions. Alberta Health Services accepts no responsibility for any modification or redistribution of this document and is not liable for any actions taken by individuals based on the information provided, or for any inaccuracies, errors, or omissions in the information in this document. These recipes are to be used as a reference and are not intended to be master formulation records. Not all recipes may be compliant with NAPRA or other standards.