||1. Triturate the hydrocortisone tablets into a fine powder and levigate with glycerin to form a paste.
2. Add portion of the normal saline, and transfer into appropriate size container.
3. Add viscous lidocaine 2%, nystatin suspension, and QS with remaining normal saline.
4. Shake until mixed well.
5. Transfer to final container and label. Refrigerate final product.
||Hydrocortisone USP powder can be used instead of tablets.
Sodium chloride 0.9% for irrigation can be used instead of injection.
Use a glycerin product as close to 100% glycerin as available.
Since no stability data available, assign beyond use date using NAPRA Guidance Document For Pharmacy Compounding Of Non-Sterile Preparations:
For Water Containing Oral Formulations: The BUD is not later than 14 days when stored at controlled cold temperatures.
Per DI Question # 20572, a mouthwash will be considered an oral formulation.
THIS FORMULATION IS NOT BASED ON LITERATURE, but is from unpublished data, historical use, or physician/pharmacy experience.
|| Amber Plastic Bottle
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|Storage/Expiry:||Refrigerator: 14 days|
|Last Date Revised:
|References:||Dr. Akabutu, UAH; Dr. Yanofsky; Cross Cancer Institute Edmonton Alberta.|
||Water-containing oral formulations – The BUD is not later than 14 days with storage at controlled cold temperatures.
National Association of Pharmacy Regulatory Authorities (NAPRA). Guidance Document For Pharmacy Compounding Of Non-Sterile Preparations. Ottawa, ON: National Association of Pharmacy Regulatory Authorities (NAPRA); 2018.
Available at: https://napra.ca/sites/default/files/documents/Mdl_Stnds_Pharmacy_Compounding_Nonsterile_Preparations_Guidance_June2018_FINAL.pdf