Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Hydrochlorothiazide Oral Suspension (LOW STRENGTH)   5 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    hydrochlorothiazide  25 mg  TAB   
    Ora-Plus® / Ora-Sweet®  1:1  SYRUP  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. In a mortar, crush tablets and triturate to a fine powder.
2. Mix Ora-Plus and Ora-Sweet together (1:1) to make vehicle.
3. Gradually levigate powder with vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes May substitute Ora-Plus® / Ora-Sweet® (1:1) with any of the following vehicles:
- Ora-Plus® / Ora-Sweet SF® (1:1)
- Ora-Blend®
- Ora-Blend SF®

Ora-Sweet SF® and Ora-Blend SF® should not be used in neonates less than or equal to 28 days corrected age.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Note Strength
  Shake Well

Storage/Expiry:Refrigerator or Room Temperature: 60 days

Last Date Revised: 23-Jun-11

References:Allen LV Jr. Erickson MA III. Stability of labetalol hydrochloride, metoprolol tartrate, verapamil hydrochloride and spironolactone with hydrochlorothiazide in extemporaneously compounded oral liquids. Am J Health-Syst Pharm 1996; 53:2304-2309.
  Hydrochlorothiazide 5 mg/mL oral suspension recipe (last updated May 2008).
SickKids Compounding Service [online recipes]. Toronto, ON: The Hospital for Sick Children. c1999 – [current date]. Available from: http://www.sickkids.ca/Pharmacy/Compounding-Service/index.html

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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