Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Cholesterol Oral Suspension    150 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    Cholesterol, USP    PWD   
    Cherry syrup       
    Ora-Plus®    SYRUP  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Weigh cholesterol powder.
2. Mix cherry syrup with a portion of Ora-Plus® and place into a metal bowl.
3. Using a spatula, add the cholesterol powder in aliquots to the syrup mixture. Manually mix until a smooth suspension is formed. (Note: an electric mixer should not be used).
4. Pour into a graduated cylinder.
5. QS to final volume with Ora-Plus®.
6. Transfer to final container and label.

Notes Can make the recipe unflavored and with a lower osmolality by using Ora-Plus instead of Cherry syrup vehicle.

Cholesterol NF is an acceptable grade for human oral use

Refer to MSDS sheet for cholesterol powder.
- May cause irritation to eyes, skin, and upon inhalation and ingestion.
- The use of an approved dust mask is recommended. Wear rubber gloves, safety glasses, and protect exposed skin.

THIS FORMULATION IS NOT BASED ON LITERATURE, but is from unpublished data, historical use or physician/pharmacy experience.

Packaging: 100 mL Amber Glass Bottle

Auxiliary Labels: Protect From Light
  Shake Well
  Store at Room Temperature

Storage/Expiry:Room Temperature: 90 days

Last Date Revised: 4-Mar-20

References:Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 6th ed. Cincinnati, OH: Harvey Whitney Books Company; 2011.

Nationwide Children's Hospital Columbus Ohio, available from https://www.nationwidechildrens.org/specialties/pharmacy-services/compounding-formulas

Personal communication from Dr. Chitra Prasad, Metabolic Disorders, Children's Hospital, London Health Sciences Centre. December, 2019.

Personal communication from Karen Walsh, Compounding Pharmacist, Sick Kids Hospital, Toronto. December, 2019.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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