Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Nitrazepam Oral Suspension    1 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    nitrazepam  10 mg  TAB   
    Water, sterile        
    HSC suspending vehicle       qs to  
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: 1. Place tablets in mortar and soak with a small amount of water for a few minutes.
2. Once sufficiently softened, levigate tablets with water to form a smooth paste.
3. Gradually levigate paste with HSC vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes See recipe for HSC Suspending Vehicle.

Other strengths of nitrazepam tablets can be used. Adjust quantity as required to make suspension.

Packaging: 100 mL Amber Plastic Bottle

Auxiliary Labels: Refrigerate
  Shake Well

Storage/Expiry:Refrigerator: 30 days

Last Date Revised: 2-Jun-11

References:
 
McCrea J, Rappaport P, Stansfield S, Baker D, Dupuis LL. James G., Extemporaneous oral liquid dosage preparations. 1st ed. Toronto, ON: Canadian Society of Hospital Pharmacists; 1988.
  Nitrazepam 1 mg/mL oral suspension recipe (last updated April 2007).
McCrea J, Rappaport P, Stansfield S, Baker D, Dupuis LL. James G., Extemporaneous oral liquid dosage preparations. 1st ed. Toronto, ON: Canadian Society of Hospital Pharmacists; 1988.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   29-Nov-2021         


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