Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Pantoprazole Oral Suspension    2 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    pantoprazole sodium  40 mg  DR TAB   
    sodium bicarbonate, USP    PWD   
    Water, sterile       qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: The tablet imprint can be removed by rubbing with a towel dampened with water. If the imprint is not removed, there may be dark flecks in the suspension.

1. In a mortar, crush tablets and triturate to a fine powder.
2. Add 85% of the total quantity of water and half the total amount of sodium bicarbonate to the mortar. Stir until the powder is dissolved (about 20 minutes).
3. Once dissolved, add remaining sodium bicarbonate and stir until mixed well.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with water.
6. Transfer to final container and label.

Notes Pantoprazole SODIUM was used in the reference and should not be interchanged with pantoprazole MAGNESIUM, since compatibility/stability data is unknown.
However, both salt forms are THERAPEUTICALLY INTERCHANGEABLE.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Protect From Light
  Refrigerate
  Shake Well

Storage/Expiry:Refrigerator: 62 days

Last Date Revised: 25-Jul-19

References:Dentinger PJ, Swenson Cf, Anaizi NH. Stability of pantoprazole in an extemporaneously compounded oral liquid. Am J Health-Syst Pharm 2002; 59:953-956.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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