Recipe - Compounding Worksheet
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These recipes are intended for use by the pharmacy manufacturing departments only.
Propylthiouracil Oral Suspension   5 mg/mL
Lot No Expiry(mm/yyyy) Ingredients Master Formula
    propylthiouracil  100 mg  TAB   
    Ora-Plus® / Ora-Sweet®  1:1  SYRUP  qs to 
Recipe Total Quantity:
Final Quantity Desired: mL

Directions: HAZARDOUS - Potential
Refer to the AHS Hazardous Medication Handling Guide for more information.

1. In a mortar, crush tablets and triturate to a fine powder.
2. Mix Ora-Plus and Ora-Sweet together (1:1) to make vehicle.
3. Gradually levigate powder with vehicle until a liquid is formed.
4. Pour into a graduated cylinder.
5. Rinse mortar and qs to final volume with vehicle.
6. Transfer to final container and label.

Notes May substitute Ora-Plus® / Ora-Sweet® (1:1) with any of the following vehicles:
- Methylcellulose 1% (preserved with parabens)/ Simple Syrup (1:1)
- Ora-Blend®

Refrigerated storage is preferred.

Packaging:  Amber Plastic Bottle

Auxiliary Labels: Can be stored at room temperature or refrigerated
  Hazardous medication - use safe handling precautions
  Shake Well

Storage/Expiry:Refrigerator: 91 days
  Room Temperature: 70 days

Last Date Revised: 17-May-18

References: AHS Hazardous Medication Handling information available on Insite: http://insite.albertahealthservices.ca/17382.asp

Nahata MC, Morosco RS.Trowbridge JM. Stability of propylthiouracil in extemporaneously prepared oral suspensions at 4°C and 25°C. Am J Health-Syst Pharm 2000; 57:1141-1143.
 
Nahata MC, Pai VB, Hipple TF. Pediatric drug formulations. 5th ed. Cincinnati, OH: Harvey Whitney Books Company; 2003.

Completed Compound Check
Lot NoDate Prepared Expiry DateTechnicianPharmacist
   6-Dec-2021         


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